Alone and in Combination, in Calves with Experimentally Induced Pneumonic Pasteurellosis.Selman IE, Allan EV, Dalgleish RG, et al: Proceedings 14th World Congress on Diseases of Cattle 1:606-610, 1986.
Protocol
Clinically healthy 10- to 12-week-old dairy calves free of detectable numbers of Pasteurella.
Calves intranasally and intratracheally challenged with Pasteurella haemolytica.
Calves randomly housed in self-contained hutches then assigned to one of four treatment groups:
Untreated
Treated with only Banamine, 2.2 mg/kg once daily for 3 days
Treated with only an antibiotic (oxytetracycline)
Treated with antibiotic (oxytetracycline) plus Banamine
Results - Antibiotic Plus Banamine
Faster, steeper reduction in mean rectal temperatures.
Significantly fewer fevers.
Highest feed intake, with steady increase in consumption.
Non-apparent gross consolidation from fibrinous pneumonia.
Calves more easily cleared the challenge organism from lower respiratory tract, as indicated by examination of the P. haemolytica isolates.